منابع مشابه
Quantification of Microbial Phenotypes
Metabolite profiling technologies have improved to generate close to quantitative metabolomics data, which can be employed to quantitatively describe the metabolic phenotype of an organism. Here, we review the current technologies available for quantitative metabolomics, present their advantages and drawbacks, and the current challenges to generate fully quantitative metabolomics data. Metabolo...
متن کاملEngineering microbial phenotypes through rewiring of genetic networks
The ability to program cellular behaviour is a major goal of synthetic biology, with applications in health, agriculture and chemicals production. Despite efforts to build 'orthogonal' systems, interactions between engineered genetic circuits and the endogenous regulatory network of a host cell can have a significant impact on desired functionality. We have developed a strategy to rewire the en...
متن کاملBiochemical Phenotypes to Discriminate Microbial Subpopulations and Improve Outbreak Detection
BACKGROUND Clinical microbiology laboratories worldwide constitute an invaluable resource for monitoring emerging threats and the spread of antimicrobial resistance. We studied the growing number of biochemical tests routinely performed on clinical isolates to explore their value as epidemiological markers. METHODOLOGY/PRINCIPAL FINDINGS Microbiology laboratory results from January 2009 throu...
متن کاملRumen microbial communities influence metabolic phenotypes in lambs
The rumen microbiota is an essential part of ruminants shaping their nutrition and health. Despite its importance, it is not fully understood how various groups of rumen microbes affect host-microbe relationships and functions. The aim of the study was to simultaneously explore the rumen microbiota and the metabolic phenotype of lambs for identifying host-microbe associations and potential biom...
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ژورنال
عنوان ژورنال: Metabolites
سال: 2016
ISSN: 2218-1989
DOI: 10.3390/metabo6040045